lazar - Lazy Structure-Activity Relationships

lazar (Lazy Structure-Activity Relationships) is a tool for the prediction of toxic activities of chemical structures. lazar derives predictions from databases with experimental toxicity data. It searches in these databases for compounds with similar structures and calculates the prediction from their measured activities.

Webinterface

Free access to lazar predictions. Please do not submit confidential information, because it travels unencrypted over the net. You can obtain predictions for confidential structures and further toxicity endpoints from www.in-silico.de. If you use lazar for scientific work, you should cite C. Helma: Lazy Structure-Activity Relationships (lazar) for the Prediction of Rodent Carcinogenicity and Salmonella Mutagenicity., Molecular Diversity 10, 147-158 (2006) [preprint] in your references.

Source code

Source code for the lazar program is available under a GNU License from in-silico's subversion repository svn://www.in-silico.de/lazar/trunk. Check it out with your svn client, e.g. svn checkout svn://www.in-silico.de/lazar/trunk your-lazar-directory and follow the instructions in the INSTALL file.

Please contact www.in-silico.de, if you need assistance or precompiled versions.

Awards

© in silico toxicology and Machine Learning Lab, financial support: Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET)