The Predictive Toxicology Challenge 2000-2001
A Workshop at the 5th European Conference on Principles and
Practice of Knowledge Discovery in Databases (PKDD 2001),
September 3 - 7, 2001, Freiburg, Germany
NEW:
Workshop related deadlines modified
NEW:Workshop schedule
NEW:
Workshop proceedings
Background
The purpose of this workshop is to discuss the
results and submissions from the Predictive
Toxicology Challenge 2000-2001. The present Predictive Toxicology Challenge is the successor
of an earlier one announced at the International
Joint Conference on AI 1997 conference. Both competitions were
inspired by the NIEHS Predictive-Toxicology Evaluation Project,
which involved contributions from human experts, expert systems,
experimental techniques and data driven methods.
The Challenge is to obtain models that
predict the outcome of biological tests for the carcinogenicity
of chemicals using information related to chemical structure
only. Details, including datasets and instructions for
submissions, can be found on the PTC
website.
Workshop Organization
This workshop shall give all
participants of the Predictive Toxicology
Challenge the opportunity to present and discuss the
submissions. Short presentations can cover methodological details
of PTC submissions or aspects of Predictive Toxicology with
general relevance. Participants interested in an oral
presentation should submit an extended abstract, no longer than
2000 words, until July 20, 2001 to helma@informatik.uni-freiburg.de
and register for the ECML/PKDD 2001 Conference. The collection of
abstracts will be published as Workshop proceedings, further
dissemination in a special issue of a journal will be discussed
at the workshop. Acceptable abstract formats are HTML, Postscript
and PDF. A large part of the workshop will be devoted to
discussions about issues which will arise during the evaluation
of the PTC submissions.
Important Dates
PTC related
Stage
|
Start
|
Finish
|
| Data Engineering |
September 01, 2000 |
March 01, 2001 |
| Model Construction |
March 02, 2001 |
June 01, 2001 |
| Model Evaluation |
June 02, 2001 |
August 15, 2001 |
Workshop
related
- Abstract deadline: July 20, 2001
- Workshop date: September 06, 2001
Chairs
C. Helma,
University Freiburg
R.D. King, University of Wales
S. Kramer, University Freiburg
A. Srinivasan, Oxford University
Organizing Committee
Romualdo Benigni, Italian
National Institute of Health
Doug Bristol,
NIEHS
Diane
Cook, University of Texas
Giuseppina Gini, Politecnico di Milano
John
Lloyd, Australian National University
Bernhard Pfahringer, University of Waikato
Ann
Richard, US EPA
Herbert Rosenkranz, University of Pittsburgh
Yin-tak Woo,
US EPA
Schedule
- 9.15-10.15: Introduction and Summary
- R. King (University of Wales), D. Bristol (US NIEHS) and S.
Kramer (University of Freiburg):
- Summary of the Predictive
Toxicology Challenge (PTC) 2000-2001
- C. Helma (University of Freiburg):
- Toxicological Background of
the PTC
- 10.45-12.45: Contributions
- H. Blockeel, K. Driessens, N. Jacobs, R. Kosala, S.
Raeymaekers, J. Ramon, J. Struyf, W. Van Laer, S. Verbaeten
(Katholieke Universiteit Leuven):
- First-Order Models for the
Predictive Toxicology Challenge 2000-2001
- H. Ohwada, M. Koyama, Y. Hoken (Science University of
Tokyo):
- ILP-based Rule Induction for
Predicting Carcinogenicity
- K.S. Ng, J.W. Lloyd, A.W. Slater (Australian National
University):
- Predictive Toxicology Using a
Decision Tree Learner
- B. Pfahringer (University of Waikato):
- (The Futility of) Trying to
Predict Carcinogenicity of Chemical Compounds
- T. Okada (Kwansei Gakuin University):
- Characteristic Substructures
and Properties in the Chemical Carcinogenicity Studied by the
Cascade Model
- V.G. Blinova, D.A. Dobrynin, S.O. Kuznetsov, E.S.
Pankratova (All-Russia Institute for Scientific and Technical
Information):
- Toxicology Analysis by Means
of Simple JSM Method
- J.F. Boulicaut, B. Cremilleux (INSA Lyon):
- Delta-Strong Classification
Rules for Characterizing Chemical Carcinogens
- T.H. Reijmers, M. Engels (Janssen Research
Foundation):
- The Application of Several
Variable Selection Methods in the Predictive Toxicology
Challenge 2000-2001
- 14.30-15.40: Evaluation
- D. Bristol (US NIEHS):
- Modeling Carcinogenicity:
Results Reflect Representation
- Y.-T. Woo (US EPA):
- Predictive Toxicology
Challenge (PTC) 2000-2001: A Toxicologist's View and
Evaluation
- 16.15-17.30: General Discussion
Links